Cell-Size Control and Homeostasis in Bacteria

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cell-Size Control and Homeostasis in Bacteria

How cells control their size and maintain size homeostasis is a fundamental open question. Cell-size homeostasis has been discussed in the context of two major paradigms: "sizer," in which the cell actively monitors its size and triggers the cell cycle once it reaches a critical size, and "timer," in which the cell attempts to grow for a specific amount of time before division. These paradigms,...

متن کامل

Cell Size Control in Bacteria

Like eukaryotes, bacteria must coordinate division with growth to ensure cells are the appropriate size for a given environmental condition or developmental fate. As single-celled organisms, nutrient availability is one of the strongest influences on bacterial cell size. Classic physiological experiments conducted over four decades ago first demonstrated that cell size is directly correlated wi...

متن کامل

Size sensors in bacteria, cell cycle control, and size control

Bacteria proliferate by repetitive cycles of cellular growth and division. The progression into the cell cycle is admitted to be under the control of cell size. However, the molecular basis of this regulation is still unclear. Here I will discuss which mechanisms could allow coupling growth and division by sensing size and transmitting this information to the division machinery. Size sensors co...

متن کامل

Stochastic Modeling of Bacterial Cell Size Control and Homeostasis

Recent studies have revealed the rules controlling cell size homeostasis in bacteria. However, whether these mechanisms apply to growth-defective backgrounds remains an open question. Herein, we propose a Markov chain model describing bacterial growth in wt or growth-defective backgrounds and test some of our predictions experimentally. Our results suggest that, in mutant backgrounds, bacteria ...

متن کامل

Cell growth and size homeostasis in silico.

Cell growth in size is a complex process coordinated by intrinsic and environmental signals. In a research work performed by a different group, size distributions of an exponentially growing population of mammalian cells were used to infer cell-growth rate in size. The results suggested that cell growth was neither linear nor exponential, but subject to size-dependent regulation. To explain the...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Current Biology

سال: 2017

ISSN: 0960-9822

DOI: 10.1016/j.cub.2017.04.028